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Giant Cell Tumor of Bone Wheeless (Visit this link)

Discussion: - a common benign but locally aggressive lesion of unknown etiology; - occurs chiefly in men between 20-50 yrs (after epiphyseal closure); - tumor is expansile lytic lesion that involves the epiphysis & metaphysis; - tumor may enlarge to occupy most of epiphysis & adjacent metaphysis; - tumor may erode & penetrate subchondral bone, articular cartilage, & cruciate ligaments;

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Added: Tue Nov 14 2006

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